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The management of polypoid dysplasia in patients with chronic ulcerative colitis has moved toward endoscopic excision and continued surveillance when the morphology of polypoid lesions allows for endoscopic resection. The current meta-analysis assessed the risk for colorectal cancer development after endoscopic resection of polyps in patients with ulcerative colitis.
From 425 articles and one Cochrane review, the authors selected 10 studies with 376 patients with inflammatory bowel disease and resected polypoid dysplasia with subsequent follow-up. Patients underwent an average of 2.8 colonoscopies during a mean surveillance period of 54.4 months. Nine cancers were observed, for a pooled incidence of 5.3 cancers per 1000 years. None of the st…