Under Just What Conditions Is Thyroid Testing During Pregnancy Indicated?

Retrospective cohort study suggests targeted testing misses many women with subclinical hypothyroidism, but how much does it matter?

The controversy continues over whom to screen and treat for hypothyroidism during pregnancy. To evaluate the efficacy of targeted screening, Swedish investigators used data and blood samples (obtained at routine ultrasound screening between 17 and 19 weeks' gestation) in a retrospective cohort study of 5254 pregnant women in Uppsala County. From 2009 through 2011, 891 of these women were screened because of personal histories of thyroid dysfunction (with or without ongoing thyroid hormone replacement), family histories of thyroid dysfunction, goiter, insulin-dependent diabetes mellitus, and other autoimmune diseases. Among 4200 untested women in the total sample, 1006 were randomly selected for thyrotropin (TSH) measurement. Endocrine Socie…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Under Just What Conditions Is Thyroid Testing During Pregnancy Indicated?

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Reviewing Author