Livedoid Vasculopathy in Chinese Patients — What's Different?

The authors note a younger age than in previous reports, as well as summer exacerbation and use of a herbal remedy.

Livedoid vasculopathy is considered to be a noninflammatory disorder characterized by small painful ulcers on the legs that heal with stellate scars. Various prothrombotic factors have been identified in these patients, some of which are acquired and some of which are inherited. Treatments have generally consisted of agents that affect coagulation.

These authors report a retrospective analysis of 24 Chinese patients seen over a 14-year period. They excluded patients with antiphospholipid antibody syndrome, vasculitis, and drug-induced disease. Some patients were tested for anticardiolipin antibodies and beta-2-glycoprotein-1 antibodies, and some were skin tested with “anaphylactogen” antigen. The authors note a younger patient age than in pr…

Reviewing Author

Jeffrey P. Callen, MD

Disclosures

Consultant / Advisory board XOMA; Eli Lilly; Celgene

Equity Various trust accounts

Editorial boards JAMA Dermatology; UpToDate

Leadership positions in professional societies Association of Professors of Dermatology (President-Elect)