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Peroral endoscopic myotomy (POEM) is an exciting innovation for treatment of achalasia. Although clinical data show strong safety and efficacy, they are largely from expert centers.
Authors of a recent white paper summarized current information from research studies, an international survey of early POEM adopters, and conference proceedings on the use, safety, and efficacy of POEM as well as recommendations for training and incorporating POEM into clinical practice. Key highlights include:
Clinical success rates are 82% to 100% in published studies comprising 1000 patients treated at expert centers, with self-limited adverse event occurrence of <10% and no mortality.
Excellent clinical efficacy is observed, but dissection might be more challen…