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Nasal oxytocin's popularity among consumers is evidenced by >200,000 Google hits, >46,000 Google scholar citations, and 175 products available on Amazon.com (accessed 8/9/14). The widespread interest, especially as a treatment for autism in children, contrasts with the paucity of repeated-dose trials in children, although single-dose studies had promising results (NEJM JW Psychiatry Dec 23 2013). In a randomized, double-blind, placebo-controlled study, researchers in Australia examined the efficacy of oxytocin nasal spray (18–24 IU) twice-daily for 8 weeks in 50 high-functioning autistic adolescent boys (age range, 12–18 years; active treatment, 26 boys; placebo, 24). Children were assessed by caregivers' and clinicians' observation measure…