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In the mid-20th century, some psychiatrists viewed schizophrenia as a result of psychological assaults that could be revealed through (if not corrected by) psychoanalysis. However, modern researchers have found that schizophrenia is highly heritable, implying that genetics are involved. The birth of modern human genetics, with gene mapping and gene sequencing, generated many studies of schizophrenia. Unfortunately, the small size of some studies, and the immaturity of bioinformatics, led to many putative genetic links of dubious validity.
In a new genome-wide association study of nearly 37,000 cases and 113,000 controls, researchers identified 108 genetic loci (83 of which have not been reported previously) linked to schizophrenia. The loci …