Secretin Improves Sensitivity of MRCP for Unexplained Pancreatitis

It also increased negative predictive value from 48% to 75%, thus reducing unnecessary ERCPs.

Magnetic resonance imaging with magnetic resonance cholangiopancreatography (MRCP) might be a useful alternative to endoscopic ultrasound (EUS) or endoscopic retrograde cholangiopancreatography (ERCP) in detecting occult malignancy and structural changes (e.g., ductal stricture, pancreas divisum) in patients with acute or acute, recurrent pancreatitis whose initial evaluation is negative. To assess whether administration of the hormone secretin improves the diagnostic accuracy of MRCP, investigators enrolled 258 patients with acute or acute, relapsing pancreatitis in an industry-funded, multicenter trial.

Patients were scheduled to undergo ERCP as part of their diagnostic evaluation. They first underwent MRCP both with and without secretin. …

Reviewing Author

Chris E. Forsmark, MD

Disclosures

Editorial boardsAmerican Journal of Gastroenterology; Gut; Pancreas

Chris E. Forsmark, MD

Disclosures

Editorial boardsAmerican Journal of Gastroenterology; Gut; Pancreas

Secretin Improves Sensitivity of MRCP for Unexplained Pancreatitis

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Reviewing Author