Medical Mystery: A Woman with Progressive Cognitive Decline and Apraxia

Jaime Toro, MD, Saúl Reyes, MD, +7 more

Jaime Toro, MD, Saúl Reyes, MD, Lisseth Burbano, MD, William T. Hu, MD, PhD, Kelly D. Watts, MS, Se Min Heo, BSc, Thomas S. Wingo, MD, Gonazalo Ucrós, MD and Manuel Yepes, MD

Nov 7, 2014

Jaime Toro, MD, Saúl Reyes, MD, +7 more

Jaime Toro, MD, Saúl Reyes, MD, Lisseth Burbano, MD, William T. Hu, MD, PhD, Kelly D. Watts, MS, Se Min Heo, BSc, Thomas S. Wingo, MD, Gonazalo Ucrós, MD and Manuel Yepes, MD

November 7, 2014

Jaime Toro, MD, Saúl Reyes, MD, +7 more

Jaime Toro, MD, Saúl Reyes, MD, Lisseth Burbano, MD, William T. Hu, MD, PhD, Kelly D. Watts, MS, Se Min Heo, BSc, Thomas S. Wingo, MD, Gonazalo Ucrós, MD and Manuel Yepes, MD

November 7, 2014

What is the diagnosis? A three-part case challenge

A 53-year-old, right-handed woman presented with a 3-year history of difficulty in expressing herself properly and understanding spoken language. Her family reported that she had felt disoriented in familiar places and was unable to recall recent events or remember names of family members. They noticed behavioral changes consisting of irritability and aggressiveness. The patient became increasingly depressed and anxious and developed a left-sided clumsiness and a mild symmetric tremor mainly affecting the hands.

Eight months before admission, the patient had myoclonic jerks in the left arm. During the 3 months before admission, she developed trouble with reading and writing. Shortly thereafter, she was unable to perform activities of daily l…

Video 2: Patient trying to fold a letter and place it in an envelope0:58

Video 4: The patient is unable to put on her jacket.0:56

Video 1: Patient trying to cross herself0:41

Video 3: The patient can't lie down on the couch.0:58

Video 5: The patient has difficulty putting on her glasses.0:41

Authors

Jaime Toro, MD

Disclosures

Editorial BoardsMultiple Sclerosis and Related Disorders

Jaime Toro, MD

Disclosures

Editorial BoardsMultiple Sclerosis and Related Disorders

Saúl Reyes, MD

Lisseth Burbano, MD

William T. Hu, MD, PhD

Kelly D. Watts, MS

Se Min Heo, BSc

Thomas S. Wingo, MD

Gonazalo Ucrós, MD

Manuel Yepes, MD

Medical Mystery: A Woman with Progressive Cognitive Decline and Apraxia

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Authors