Although new guidelines recommend statin use in more HIV-infected patients, most of those with evidence of coronary plaque are still not flagged as needing therapy.
Cholesterol guidelines released in 2013 recommend statin therapy for, among others, patients aged 40 to 75 with a 10-year atherosclerotic cardiovascular disease (CVD) risk ≥7.5%, as estimated by a new calculator. Whether this recent guideline, which was designed for the general population, is better than the 2004 Adult Treatment Panel III guidelines at predicting CVD — or at appropriately recommending statin use — in HIV-infected patients is not known. Now, investigators have examined the performance of the new and old guidelines in a cohort of HIV-infected patients.
A total of 108 patients without known CVD underwent coronary computed-tomography angiography (CCTA). The median age was 46 years, 50% were current smokers, and 20% were receivin…
Reviewing Author
DisclosuresGrant/Research SupportNIH
Editorial BoardsUpToDate; ID Images (idimages.org); Infectious Diseases Society of America COVID-19 Treatment Guidelines; International Antiviral Society–USA (Guidelines Committee)
Leadership Positions in Professional SocietiesHIV Medicine Association; Infectious Diseases Society of America (Board of Directors)
DisclosuresGrant/Research SupportNIH
Editorial BoardsUpToDate; ID Images (idimages.org); Infectious Diseases Society of America COVID-19 Treatment Guidelines; International Antiviral Society–USA (Guidelines Committee)
Leadership Positions in Professional SocietiesHIV Medicine Association; Infectious Diseases Society of America (Board of Directors)