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Clinicians and patients are increasingly concerned about cumulative radiation exposure from medical testing. Researchers in Switzerland used a special reconstruction technique in coronary computed tomographic angiography (CTA) to lower radiation exposure to <1 millisievert (mSv) in 36 patients who underwent both coronary CTA and invasive coronary angiography (ICA).
Mean radiation dose with CTA was 0.29, and 97% of coronary segments were deemed interpretable. Compared with ICA, CTA's sensitivity and specificity for substantial epicardial disease (defined as ≥50% luminal narrowing) were 100% and 74%, respectively, per patient, and 85% and 86%, respectively, per vessel; per-patient positive predictive value and negative predictive value were 77…