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Dengue is among the most common arboviral infections worldwide and is endemic in many tropical regions. Outside of endemic areas, dengue viral infections are seen primarily in individuals with recent travel to endemic areas as well as in rare autochthonous outbreaks. Dengue is a flavivirus and is closely related to viruses known to have significant neurological involvement, such as West Nile virus, Japanese encephalitis virus, and St. Louis encephalitis virus.
Researchers compared clinical factors and outcomes among dengue patients with no neurologic involvement, those with central nervous system (CNS) involvement, and those with peripheral nervous system (PNS) involvement in a hospital-based, prospective cohort study of 486 adults and child…