Low DHEA Predicts Risk for Coronary Heart Disease

But would screening for this steroid improve patient outcomes?

The controversy regarding the role of sex steroids in cardiovascular disease continues. This study has addressed whether dehydroepiandrosterone (DHEA) and its sulfated form (DHEA-S) could predict major coronary heart disease (CHD) or cerebrovascular disease (CBVD) events in 2416 elderly men participating in the prospective, population-based Osteoporotic Fractures in Men study in Sweden (age range, 69–81).

Clinical outcomes data on the participants were obtained from national Swedish registries on hospital discharge and cause of death. Major CHD events were hospitalization for acute myocardial infarction, unstable angina, or revascularization; or death from CHD. CBVD events studied were hospitalization for stroke or transient ischemic attack,…

Reviewing Author

JoAnne M. Foody, MD

Disclosures

Consultant / Advisory boardAegerion; Amarin; Bristol-Myers Squibb; Janssen; Merck; Pfizer; Sanofi-Aventis; Boehringer Ingelheim

Leadership positions in professional societiesAmerican College of Cardiology, Cardiosmart (Co-chair)

JoAnne M. Foody, MD

Disclosures

Consultant / Advisory boardAegerion; Amarin; Bristol-Myers Squibb; Janssen; Merck; Pfizer; Sanofi-Aventis; Boehringer Ingelheim

Leadership positions in professional societiesAmerican College of Cardiology, Cardiosmart (Co-chair)

Low DHEA Predicts Risk for Coronary Heart Disease

Topics

Reviewing Author