Chronic Graft-Versus-Host Disease with Eruptive Angiomas

Researchers suggest the name GVHD-associated angiomatosis for what they consider a distinct entity.

Graft-versus-host disease (GVHD) is a major complication of hematopoietic cell transplantation involving multiple sites. It has an acute and a chronic phase (cGVHD); transplant recipients may experience one, both, or neither. Some patients with chronic disease have cutaneous manifestations. These authors describe an unusual presentation of cGVHD with eruptive angiomas.

They identified 11 patients with cGVHD who developed vascular proliferations a median of 4 years after allogeneic hematopoietic stem-cell transplantation (mean age, 53; slight female predominance). Clinical and pathologic review revealed sclerotic cGVHD in all patients; an acute phase was documented in seven. Lesions (papules, nodules, and tumors) had a tendency to bleed and a…

Reviewing Author

Angelica Selim, MD

Disclosures

Grant / Research support NIH/NCI, The Plastic Surgery Foundation

Angelica Selim, MD

Disclosures

Grant / Research support NIH/NCI, The Plastic Surgery Foundation

Chronic Graft-Versus-Host Disease with Eruptive Angiomas

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Reviewing Author