Thrombolysis Within 1 Hour of Symptom Onset in a Mobile Stroke Unit

German investigators increased the proportion of patients receiving lysis within 1 hour, but there was no outcome benefit.

German investigators previously reported results from a project in which a “stroke emergency mobile unit” (STEMO) was deployed (NEJM JW Emerg Med Apr 22 2014). The STEMO is an ambulance that is equipped with a computed tomography scanner and staffed by a neurologist. In this substudy, the investigators compared the proportion of patients who received thrombolysis within 1 hour between patients who received STEMO and patients who received routine care.

Among 530 patients receiving thrombolysis, it was administered within 1 hour in 31% of STEMO patients versus 5% of routine-care patients. Mortality in the two groups was equivalent. Functional outcomes were not reported.

Reviewing Author

Daniel J. Pallin, MD, MPH

Disclosures

Consultant/Advisory BoardPortola Pharmaceuticals, Inc.

Speaker’s BureauPeerView Institute for Medical Education

Grant/Research SupportAgency for Healthcare Research and Quality; CDC; NIH–National Center for Advancing Translational Sciences; NIH–National Institute of Allergy and Infectious Diseases (NIAID); NIH–NIAID–Antibacterial Resistance Leadership Group; Merck; Pfizer; Boehringer-Ingelheim; Shire; Portola Pharmaceuticals, Inc.; Novartis; bioMérieux; Siemens; Rapid Pathogen Screening; Magnolia; Stago; Innovative Biosensors; Molecular Detection, Inc.; Dyax Corp.; Trius Pharmaceuticals

Daniel J. Pallin, MD, MPH

Disclosures

Consultant/Advisory BoardPortola Pharmaceuticals, Inc.

Speaker’s BureauPeerView Institute for Medical Education

Thrombolysis Within 1 Hour of Symptom Onset in a Mobile Stroke Unit

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Reviewing Author