Indoor Residual Spraying plus Treated Bed Nets vs. Treated Bed Nets Alone: No Advantage

Adding indoor residual spraying to use of long-lasting insecticide–treated bed nets did not significantly reduce incidence of clinical malaria or density of vector mosquitoes.

Long-lasting insecticidal nets (LLINs) and indoor residual spraying are effective tools in malaria-control programs. To assess whether adding indoor residual spraying with dichlorodiphenyltrichloroethane to LLIN use improves protection against malaria, investigators conducted a cluster-randomized trial in a rural area of the Gambia with moderate seasonal malaria transmission.

Seventy clusters of villages were randomized to LLIN alone or LLIN plus indoor residual spraying. The primary endpoints — clinical malaria in children aged 6 months to 14 years and vector mosquito density — were measured over 2 years. In both groups, LLIN coverage was high (89%–92% in year 1, 93%–96% in year 2); in the LLIN-plus-spraying group, >80% coverage with sprayi…

Reviewing Author

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Indoor Residual Spraying plus Treated Bed Nets vs. Treated Bed Nets Alone: No Advantage

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Reviewing Author