In Vitro Fertilization Is Generally Safe in the U.S.

Complications occur infrequently during autologous cycles and are even more uncommon during donor cycles.

As in vitro fertilization (IVF) becomes more common in the U.S., estimating the risks associated with assisted reproductive technology (ART) becomes more precise. Using National ART Surveillance System data that included 97% of cycles and 94% of ART clinics, CDC investigators calculated IVF complication rates associated with more than 1,135,000 autologous cycles and 112,000 donor cycles from 2000 through 2011.

Rates of any complication were 131.8 and 27.3 per 10,000 autologous and donor cycles, respectively. The most common complication was ovarian hyperstimulation syndrome (OHSS), occurring at rates of 121.2 and 22.0 per 10,000 autologous and donor cycles, respectively. Hospitalization was required in 28.2 per 10,000 autologous cycles and 6…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

In Vitro Fertilization Is Generally Safe in the U.S.

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Reviewing Author