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Observational studies show that obstructive sleep apnea (OSA) is more prevalent in patients with asthma than in those without. This study provides additional evidence for that association in a population-based cohort.
In the Wisconsin Sleep Cohort Study, 1521 randomly chosen state employees were followed from 1988 to 2013; participants underwent overnight polysomnography every 4 years. Among 81 participants with asthma whose sleep studies were normal at baseline, 22 (27%) developed OSA (defined by an apnea-hypopnea index of ≥5 events per hour), whereas 245 participants without asthma (17%) developed OSA. Relative risk for new-onset OSA was 1.39 in asthmatic participants and was independent of body-mass index.