Shorter Treatment May Be Sufficient for Candida Osteoarticular Infections

In a case series, all 19 patients with follow-up data were cured with aggressive surgical debridement and antifungal therapy administered for a median of 45 days.

Candida osteoarticular infections are rare. Such infections may occur in immunocompromised patients following fungemia, and occasionally as a complication of orthopedic surgery. Current U.S. and European guidelines recommend surgical debridement and 6 to 12 months of antifungal therapy — but is such lengthy treatment really necessary?

To shed light on this topic, researchers reviewed the records of patients who were treated for Candida osteoarticular infections at a single New York hospital between 1988 and 2012.

The 23 patients were aged 22 to 83 (median, 62). Nine were immuncompromised (diabetes mellitus in 4; chronic immunosuppressive therapy in 3; dialysis, HIV infection, and hematologic malignancy in 1 each). Thirteen of the infections w…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Shorter Treatment May Be Sufficient for Candida Osteoarticular Infections

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Reviewing Author