Updated Data on Risk for Uterine Perforation and Contraceptive Failure with IUD Use

Intrauterine devices (IUDs) are effectively used by a growing number of U.S. women, yet some remain concerned about the safety of IUDs, particularly regarding the potential for uterine perforation. To assess the safety and effectiveness of IUDs releasing 0.02 mg levonorgestrel (LNG) daily compared with assorted copper IUDs, industry-funded researchers conducted a large prospective cohort study in six European countries.

Among >61,000 new users of LNG-releasing or copper IUDs, 81 uterine perforations were reported within the first year, none of which led to any serious injury of intra-abdominal or pelvic structures. For all IUDs, perforation was 6 times more common with breast-feeding. Although all IUDs were highly effective, contraceptive fa…