Early Valve Surgery in Staphylococcal Prosthetic Valve Endocarditis: Still Case-by-Case

In an observational study of 168 patients with left-sided staphylococcal prosthetic valve endocarditis, early valve surgery was not an independent predictor of 1-year mortality.

Staphylococcus aureus prosthetic valve infectious endocarditis (SA-PVIE) has a mortality rate of 40% to 80%. Several reports have suggested reduced in-hospital mortality among individuals who undergo early valve replacement surgery (EVS), prompting some authors to recommend EVS for all patients with SA-PVIE. However, other investigators believe that decisions regarding EVS should be made on a case-by-case basis.

In an attempt to rectify this discrepancy, researchers analyzed data from a prospective, multicenter, multinational cohort of patients with infective endocarditis treated between 2000 and 2006. A total of 168 patients with left-sided SA-PVIE were identified; 74 of them underwent EVS.

Compared with the patients who did not receive the …

Reviewing Author

Neil M. Ampel, MD

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Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Early Valve Surgery in Staphylococcal Prosthetic Valve Endocarditis: Still Case-by-Case

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Reviewing Author