CABG vs. PCI for Multivessel CAD: Do Second-Generation Stents Make a Difference?

Second-generation stents narrow the gap between the two revascularization strategies for nondiabetic patients with multivessel disease.

For multivessel coronary artery disease (CAD), coronary artery bypass grafting (CABG) generally has lower rates of myocardial infarction (MI) and repeat revascularization than percutaneous coronary intervention (PCI), even with drug-eluting stents (DESs); CABG also has shown a trend toward better survival as CAD complexity increases but a higher rate of stroke. Two manufacturer-supported studies reexamine this issue in the era of safer, more-effective second-generation DESs.

In a noninferiority, multicenter study, 880 Asian patients with multivessel CAD (77% with 3-vessel) were randomized to CABG or PCI with everolimus-eluting stents (EESs). The study was stopped prematurely due to slow enrollment. PCI patients received an average of 3.4 ste…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI

Leadership Positions in Professional SocietiesHeart Valve Collaboratory (Scientific Committee Member, Chair of the Publications Committee)