For nearly a quarter of their observation time, patients had HIV viral loads >1500 copies/mL, which has important implications for transmission.
Although a large proportion of patients in care are virologically suppressed on antiretroviral therapy (ART), rebounds occur. Such rebounds can have important implications both for individual health and for HIV transmission risk. Now, in an observational study involving HIV-infected patients in care at any of six clinics in the U.S. between April 2009 and March 2013 who, as part of routine medical care, had two or more viral load tests >30 days apart, researchers calculated the proportion of time the patients' viral loads were >1500 copies/mL (considered to be a threshold for heterosexual transmission).
A total of 14,532 patients were involved (31% men who have sex with men, 34% women; 64% black; 70% aged ≥40 years). During the study period,…
Reviewing Author
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)