Is NEDA (No Evidence of Disease Activity) in Multiple Sclerosis a Realistic Treatment Goal?

As multiple sclerosis (MS) therapeutic options become more numerous, putting MS inflammation into remission has become a stated treatment goal. No evidence of disease activity (NEDA) includes no relapses, no worsening disability, and no new lesions on magnetic resonance imaging (MRI). Several clinical trials have examined NEDA status. In this study, researchers assessed NEDA within an academic practice, with a cohort of 215 patients with relapsing remitting multiple sclerosis (MS) enrolled from the year 2000 through 2005. Participants underwent clinical assessments every 6 months and annual MRIs for 7 years. The study was manufacturer sponsored. NEDA was achieved in 46% of patients at 1 year, 28% of patients at 2 years, and only 8% of patie…