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Only 20% to 30% of people at clinical high risk (CHR) for schizophrenia develop psychosis within 3 years. The strongest predictors are severity of symptoms — especially negative ones — and subthreshold thought disorder. Emotion recognition is impaired in individuals with schizophrenia, starting early in the illness. Now, researchers have examined emotion-recognition deficits as a potential predictor of transition to psychosis.
The participants, 49 individuals aged 13 to 28 at CHR for schizophrenia and 31 healthy controls, completed emotion-recognition measures. Within 2.5 years, 7 CHR participants developed schizophrenia (CHR+ participants) and 42 did not (CHR− participants). The three groups did not differ significantly by sex (57%–76% male…