In infants aged <3 months with both bacteremia and culture-proven UTI, the urinalysis was highly sensitive for diagnosing UTI.
Urinary tract infection (UTI) is the most common infection in febrile neonates. Infants with a negative urinalysis (UA) and a positive urine culture are considered to have a UTI. Previously, the sensitivity of the UA for the diagnosis of UTI was considered poor, in the 75% to 85% range.
To determine the sensitivity and specificity of UA for UTI, researchers conducted a multicenter, cross-sectional analysis of infants aged <3 months who had the same pathogenic organism isolated in both blood and urine. Sensitivity was calculated on infants who had at least a partial UA performed and had ≥50,000 colony-forming units per milliliter from the urine culture. Specificity was determined using data from a random sample of infants who had negative uri…
Reviewing Author
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)