Recovery of Enteral Autonomy in Infants with Intestinal Failure

More than 40% of infants with bowel failure were returned to enteral autonomy without transplantation.

Intestinal failure (IF) in neonates is a serious condition that can lead to dependence on parenteral nutrition (PN) and/or intestinal transplantation. In a multicenter, retrospective review, investigators assessed the incidence of enteral autonomy (EA) and predictors of its recovery among 272 infants with diagnoses of IF who required >60 days of PN. The most common etiologies of IF were necrotizing enterocolitis (NEC), gastroschisis, small bowel atresia, and volvulus.

After a median follow-up of 3 years, 43% achieved enteral autonomy, defined as freedom from PN for >3 months, 13% remained dependent on PN, and 43% had died, undergone intestinal transplantation, or both. Infants with EA were more likely to have had NEC, preserved ileocecal val…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Recovery of Enteral Autonomy in Infants with Intestinal Failure

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Reviewing Author