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With improved survival, more women with congenital heart disease (CHD) are at risk for pregnancy. Investigators used a nationwide U.S. database from 2000 through 2010 to identify delivery hospitalizations in women with and without CHD (10,700 and 12,500,000, respectively). During the study period, CHD prevalence increased from 6.4 to 9.0 per 1000 deliveries. The most common types of congenital heart lesions included septal defects and valvular lesions. Disorders of pulmonary circulation were present in 3% of women with CHD. Incidence of maternal death, need for mechanical ventilation, and a composite cardiovascular outcome (including events such as myocardial infarction, cardiac arrest, and stroke) were higher among women with CHD. A variet…