Young people age at different rates, and those who are biologically older have more problems in functioning.
If we want to prevent age-related diseases, we will need to intervene quickly, even before disease is manifest. To determine if the aging process can be detected in people without chronic disease, researchers analyzed data from a prospective study of a birth cohort of 1037 regularly assessed individuals.
Biologic age was assessed at chronological age 38 with a 10-item algorithm from the National Health and Nutrition Examination Survey. Pace of aging from age 26 to 38 was assessed with 18 measures covering cardiovascular, metabolic, renal, hepatic, respiratory, and immune function; dental health; and telomere length. Physical functioning, cognition, and appearance were also assessed at age 38.
The pace of aging was normally distributed, rangin…
Reviewing Author
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)