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Cardiac troponin testing is useful in risk-stratifying patients with acute coronary syndromes. To determine if it also might be prognostic for patients with stable ischemic heart disease (IHD), investigators conducted an ancillary study of the BARI 2D trial (NEJM JW Cardiol Jul 2009and N Engl J Med 2009; 360:2503), in which patients with both stable IHD and type 2 diabetes were randomized to percutaneous coronary intervention or coronary artery bypass grafting.
Of 2285 patients, 39% had baseline high-sensitivity troponin T levels that the authors classified as abnormal (≥14 ng/L). At a median follow-up of 5 years, these patients had significantly higher incidence of myocardial infarction, stroke, or death from cardiovascular causes (the comp…