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Handwashing is recommended to prevent infection transmission, yet few rigorous studies supporting it have been published. In an open-label, randomized trial conducted over 3 years, investigators assessed whether a Web-based intervention to increase handwashing, monitor handwashing activity, and provide feedback would decrease the number of acute respiratory infections over a subsequent 16-week winter period. Participants (16,908 adults) were recruited from general practices in England. The intervention included four sessions; most participants completed at least part of all four. The intervention group received automated e-mail reminders and had access to special Web pages.
Based on participant-completed questionnaires, 51% of the interventi…