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Acute ischemic stroke can be a challenging diagnosis due to the plethora of possible neurological symptoms and signs and the fact that radiologic studies (especially computed tomography) may be negative in the first hours. Consequences of a missed stroke diagnosis have not received much attention. These authors retrospectively analyzed 2200 patients from the Lausanne Acute Stroke Registry, of whom 47 (2.1%) were initially misdiagnosed.
Patients with an initial misdiagnosis were likely to be younger and to have lower diastolic blood pressure. Clinical features that were significantly more common in misdiagnosed patients than in correctly diagnosed stroke patients were lack of eye deviation (odds ratio, 0.21) and cerebellar stroke (OR, 3.78). …