In a single-center prospective cohort study, survivors of both lobar and nonlobar intracerebral hemorrhage had lower rates of recurrence if their blood pressure was successfully controlled.
Treatment of hypertension reduces the risk for intracerebral hemorrhage (ICH). However, we do not know the optimal blood pressure target for patients who have survived an ICH. This is especially true for lobar ICH, which has a different pathophysiology than nonlobar ICH and affects older patients, in whom the risk-benefit ratio of antihypertensive therapy remains controversial. To address this uncertainty, investigators studied the relationship between blood pressure and recurrent ICH.
Between 1994 and 2011, the authors prospectively enrolled 1145 patients with spontaneous ICH seen at one academic medical center. Investigators blinded to clinical information classified ICH as lobar or nonlobar based on radiographic characteristics and follow…
Reviewing Author
DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)
DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)