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Staphylococcus aureus can be isolated from lesional skin in at least 80% of patients with atopic dermatitis whether or not the skin looks “infected.” Crusting hints at high levels of colonization. At some point, heavy colonization contributes to disease severity and persistence. Although antistaphylococcal antibiotics are often prescribed, bathing the skin in tap water may wash off crusts and bacteria to reduce the density of S. aureus. Recently, sodium hypochlorite (NaOCl) bleach baths have become fashionable, added to bathwater. Do bleach baths really work better than regular baths?
In a double-blind, placebo-controlled, crossover trial, 40 children aged 4 to 18 years with moderate-to-severe atopic dermatitis were randomized to bleach bath…