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The Mediterranean diet (MeD), with its emphasis on plant-based foods, fish, and olive oil, has cardiovascular benefits; limited evidence also suggests the MeD can lower incidence of cancer. To examine the effect of the MeD on breast cancer incidence, researchers in Spain conducted a secondary analysis of a large randomized trial originally designed to assess cardiovascular effects of the MeD (supplemented either with extra-virgin olive oil [EVOO] or nuts) versus a conventional reduced-fat diet in persons at high cardiovascular risk (NEJM JW Gen Med Apr 1 2013 and N Engl J Med 2013; 368:1279). Participants included 4282 white women (mean baseline age, 68). The trial was stopped after a median of 4.8 years because of cardiovascular benefit.
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