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Serum testosterone levels should be monitored periodically in patients who apply topical testosterone. To learn more about variability in testosterone measurements taken on different days or at different times of day, U.S. researchers studied 47 men (age, ≥65) with low testosterone levels (<275 ng/dL) who received either testosterone gel or placebo gel for 4 months*.
Testosterone levels were measured at three visits. At the first two visits, gel was applied at 8:00 a.m., and blood was drawn at 10:00 a.m. The third “visit” was admission to a clinical research unit, where eight blood levels were obtained during a 24-hour period (including 2 hours after 8:00 a.m. application of gel). The following results were noted:
Among testosterone recipient…