Prevalence of Reduced Leaflet Motion After Aortic Valve Replacement and Risk for Stroke

Stick to warfarin during the first 3 months.

The 2007 European Society for Cardiology guidelines on managing valvular heart disease recommend oral anticoagulation for the first 3 months after insertion of bioprostheses. However, low-dose aspirin is widely used as an alternative despite the lack of randomized studies supporting its safety. Now, the question of optimal antithrombotic therapy after aortic-valve replacement (AVR) becomes fundamental because of a disturbing rate of subclinical leaflet thrombosis, especially when dual antiplatelet therapy (DAPT) has been selected.

Researchers examined prevalence of reduced leaflet motion in a manufacturer-sponsored clinical trial of transcatheter AVR (TAVR) and in two single-center registries of patients undergoing TAVR or surgical AVR. Redu…

Reviewing Author

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)

Prevalence of Reduced Leaflet Motion After Aortic Valve Replacement and Risk for Stroke

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Reviewing Author