Hepatitis B virus infection is more common in HIV-infected than HIV-uninfected men who have sex with men and less common in the combination ART era than earlier.
Men who have sex with men (MSM) have a disproportionately high hepatitis B virus (HBV) infection rate — 15% to 25% of new HBV infections in the U.S. occur in this group. Despite the availability of an effective vaccine and decades-old recommendations that MSM be vaccinated, uptake remains low. Some antiretrovirals have anti-HBV activity, but the effect of antiretroviral therapy (ART) on incident HBV infection remains unknown. Now, investigators have studied incident HBV infection among HIV-infected and HIV-uninfected MSM in the MACS cohort.
Among 6972 men enrolled through 2003, 2375 (75% HIV-uninfected) tested negative for HBV at study entry and had one or more follow-up visits. Thirty-one percent (41% of HIV-infected and 28% of HIV-uninfect…
Reviewing Author
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)