IV Lidocaine for Renal Colic: Not Ready for Prime Time

Lidocaine did not help with pain but seemed to help with nausea.

Intravenous (IV) lidocaine has analgesic properties. Investigators in a single Iranian emergency department randomized 110 patients with renal colic to receive IV morphine (0.1 mg/kg) plus either lidocaine (1.5 mg/kg) or normal saline.

Patients rated pain and nausea on a visual analog scale before treatment and repeatedly for 2 hours after. There was no difference between the lidocaine and saline groups in pain relief, but median time to being nausea free was superior in the lidocaine group (27 vs. 58 minutes).

Reviewing Author

Daniel J. Pallin, MD, MPH

Disclosures

Consultant/Advisory BoardPortola Pharmaceuticals, Inc.

Speaker’s BureauPeerView Institute for Medical Education

Grant/Research SupportAgency for Healthcare Research and Quality; CDC; NIH–National Center for Advancing Translational Sciences; NIH–National Institute of Allergy and Infectious Diseases (NIAID); NIH–NIAID–Antibacterial Resistance Leadership Group; Merck; Pfizer; Boehringer-Ingelheim; Shire; Portola Pharmaceuticals, Inc.; Novartis; bioMérieux; Siemens; Rapid Pathogen Screening; Magnolia; Stago; Innovative Biosensors; Molecular Detection, Inc.; Dyax Corp.; Trius Pharmaceuticals

Daniel J. Pallin, MD, MPH

Disclosures

Consultant/Advisory BoardPortola Pharmaceuticals, Inc.

Speaker’s BureauPeerView Institute for Medical Education

IV Lidocaine for Renal Colic: Not Ready for Prime Time

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Reviewing Author