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NEJM Journal Watch Infectious Diseases continues to forge informative links between key research and clinical practice, but with a new twist: Our coverage of HIV/AIDS now has its own domain within the realm of infectious diseases. That said, HIV infection was the hottest topic in 2015, garnering 6 of our top 10 stories.
The START study was by far the number one story; this large, multinational trial provided compelling evidence that antiretroviral therapy (ART) should be initiated in all HIV-infected individuals regardless of CD4-cell count. The other HIV/AIDS selections addressed a variety of clinical issues, including the importance of retention in care for curbing transmission, recognition of primary HIV, the outbreak of HIV among persons…