Colonization with Ciprofloxacin-Resistant Escherichia coli in Healthy Children and Mothers

Approximately 20% of mothers or their twin children had stool colonization with resistant strains, and antibiotic exposure was not an identified risk factor for colonization.

Although resistance to various antibiotics among Escherichia coli isolates is well recognized, colonization studies in healthy individuals are limited. To examine the proportion of young children with ciprofloxacin-resistant E. coli, investigators from two medical centers in St. Louis prospectively analyzed stool samples from 40 women with twin pregnancies. Stools were collected semiannually in the women. Samples were collected monthly to age 2 years and bimonthly thereafter in the twins for a median of 890 days (interquartile range, 678–1118 days). Ciprofloxacin resistance was defined as growth from samples cultured on MacConkey agar containing ciprofloxacin. In addition, strains were characterized by both multilocus sequence typing and pa…

Reviewing Author

Larry M. Baddour, MD

Disclosures

RoyaltiesUpToDate, Inc. (Authorship duties)

Larry M. Baddour, MD

Disclosures

RoyaltiesUpToDate, Inc. (Authorship duties)

Colonization with Ciprofloxacin-Resistant Escherichia coli in Healthy Children and Mothers

Topics

Reviewing Author