A New Blood Pressure Target for High-Risk Patients?

In SPRINT, adverse cardiovascular events occurred less frequently when the systolic BP treatment target was 120 mm Hg.

In the 2010 ACCORD blood pressure trial, treating hypertensive diabetic patients intensively to reach a systolic blood pressure (BP) target of <120 mm Hg did not improve outcomes compared with treatment to a standard target of 140 mm Hg (NEJM JW Gen Med Apr 15 2010 and N Engl J Med 2010; 362:1575). Now, in the randomized Systolic Blood Pressure Intervention Trial (SPRINT), researchers compared the same targets in 9361 high-risk nondiabetic hypertensive patients.

To enroll in SPRINT, patients were required to have known cardiovascular (CV) disease, 10-year Framingham risk score >15%, reduced glomerular filtration rate, or age ≥75. Average systolic BP during the trial was 121.5 mm Hg in the intensive group and 134.6 mm Hg in the standard group…

Author

Allan S. Brett, MD

Disclosures

Nothing to disclose

Allan S. Brett, MD

Disclosures

Nothing to disclose

A New Blood Pressure Target for High-Risk Patients?

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