Early Experience with Brain Hemorrhage During Novel Oral Anticoagulant Use

An observational study shows that OAC-related brain hemorrhage remains a challenge.

Intracerebral hemorrhage (ICH) associated with oral anticoagulant (OAC) use is a concern. Mortality with ICH while taking warfarin ranges from about 30% to 60%. The characteristics and outcomes for patients with ICH while taking novel oral anticoagulants (NOACs) is less clear. These authors conducted a multicenter registry study at 38 stroke units across Germany. They investigated mortality, neurological status at 3 months, and frequency of hematoma expansion.

During a 3-year period, 61 patients (mean age, 76.1 years; 41% women; 97% with atrial fibrillation) were enrolled in the registry. Patients had moderate deficits at the time of admission (median NIH Stroke Scale score, 10). The mean ICH volume was 10.8 cc; 41% of the hemorrhages were l…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Early Experience with Brain Hemorrhage During Novel Oral Anticoagulant Use

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Reviewing Author