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Clinicians and patients would benefit from the identification of early schizophrenia symptoms. To learn more about early symptoms, researchers cross-referenced a national hospitalization database in Israel with data from mandatory psychological and functional assessments of draft eligibility in 723,316 Israeli males aged 16 to 17 (mean follow-up, 10 years).
The data provided pre-illness information about functioning in 3929 individuals who were eventually hospitalized for schizophrenia. The investigators compared 1659 of these individuals plus a matched nonaffected sibling with 167,616 well sibling pairs.
Social activity (ability to make and maintain friends), independent behavior (ability to make decisions and resolve conflict in interaction…