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“Reducing to zero” the rate of central-line–associated bloodstream infections (CLABSIs) requires optimizing not only the approach to catheter insertion, but also the approach to maintaining the catheters. One recently invented approach to decrease CLABSI rates is the use of catheter-port antiseptic barrier caps that contain an antiseptic-impregnated sponge that initially disinfects the port hub during placement and thereafter physically covers the hub. Investigators have now performed a multiphase prospective trial to assess the efficacy of antiseptic barrier caps in reducing rates of CLABSIs and blood culture contamination in a single tertiary-care cancer center.
The introduction of disinfection caps was associated with a significant decrea…