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Urine specimens for diagnosis of urinary tract infection (UTI) in infants are often difficult to obtain and interpret. Classic definitions of UTI require ≥100,000 colony-forming units (CFU)/mL of a single bacterial organism, although recent recommendations accept fewer bacteria, and any bacterial growth in urine collected by suprapubic aspiration (SPA) is often accepted as diagnostic. In a retrospective study of 430 infants (age range, 5 days to 12 months; 64% boys) with symptomatic urinary infection diagnosed by SPA at a Swedish children's hospital between 1994 and 2003, investigators compared clinical parameters between those with urinary bacterial counts <100,000 CFU/mL (low-count group) and ≥100,000 CFU/mL (high-count group).
Overall, 19…