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A growing body of evidence suggests that interrupting prolonged sitting with intermittent brief periods of standing or light exercise can improve glucose metabolism (NEJM JW Gen Med Jul 1 2012 and Diabetes Care 2012; 35:976). Researchers provide additional evidence in this study of 22 overweight postmenopausal women with prediabetes.
Participants were involved in three 7.5-hour experimental sessions conducted at a U.K. diabetes center: sitting only; sitting punctuated by 5 minutes of standing every 30 minutes; and sitting punctuated by 5 minutes of walking on a treadmill (mean speed, 3 km/hour) every 30 minutes. At each session, participants ate a standardized breakfast and lunch, and blood was sampled frequently postprandially.
Mean incremen…