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Limited, flawed evidence underlies the recommendation that couples wait ≥3 months after an early pregnancy loss (i.e., <20 weeks' gestation) before attempting to conceive again. In a secondary analysis of a trial of preconception aspirin use among women with histories of pregnancy loss, investigators capitalized on the availability of self-reported data about timing of pregnancy attempts (not just the actual pregnancy events). Birth outcomes were stratified according to whether subsequent pregnancy was attempted within 3 months or longer than 3 months after early pregnancy loss or termination.
Of 1083 women, 77% attempted another pregnancy within 3 months of an early loss. Compared with women who waited longer, those who started trying to co…