Cancer Survivors Can Achieve Pregnancy with Oocyte Cryopreservation, but Births Remain Uncommon

Probabilities of success are still impossible to estimate.

Oocyte cryopreservation is presented to young women with cancer as one approach to preserving their reproductive potential before gonadotoxic therapy. Still, only about 3000 live births have been reported worldwide (and very few of them in cancer survivors). In a retrospective study, researchers at one university-based infertility center documented the efficacy of this treatment between 2005 and 2014.

In all, 176 women (median age, 31; 75 with breast cancer, 51 with gynecologic cancer, 32 with hematologic cancer, 18 with other malignancies) completed 182 oocyte cryopreservation cycles before beginning cancer therapy. Median time from consult request to oocyte retrieval following ovarian stimulation was 12 days. Overall, a median of 15 oocyte…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Cancer Survivors Can Achieve Pregnancy with Oocyte Cryopreservation, but Births Remain Uncommon

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Reviewing Author