Small Sessile Serrated Polyp Is Associated with Advanced Neoplasia at Colonoscopy Follow-Up

Current recommendations for surveillance of sessile serrated polyps (SSPs) treat them much like conventional adenomas. SSPs <10 mm in size without cytological dysplasia are considered low-risk lesions. However, the data available to guide surveillance recommendations for patients with SSPs are quite limited.

In the current single-center study, colonoscopy data were retrieved from 2260 consecutive patients who had an adenoma or SSP on pathology between 2005 and 2011. Of these, 788 who had follow-up examinations at the same center were characterized by their risk for advanced neoplasia at follow-up based on initial pathology findings. High risk was defined as ≥3 adenomas (including SSP if present) or an adenoma ≥10 mm with villous elements or …