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The Eosinophilic Esophagitis Endoscopic Reference Score (EREFS) was recently developed to help standardize reporting of endoscopic findings in patients with eosinophilic esophagitis (EoE; Gut 2013; 62:489). The score takes into account the presence of esophageal edema and strictures and the presence and severity of exudates, rings, and furrows.
To assess the diagnostic accuracy of the score and its responsiveness to treatment among patients with EoE, researchers conducted a prospective cohort study of consecutively enrolled adults undergoing outpatient upper endoscopy who had symptoms of esophageal dysfunction. Patients who received a diagnosis of EoE (per consensus guidelines) were then treated with topical steroids or dietary elimination a…